- Bills fall to heating up Colts
- Kamara knee injury, questionable for Week 12
- Thanksgiving Night Football
As the eleventh week of the National Football League comes to a conclusion, teams look to review Week 11 game footage, improve, and get ready for the following week. On Sunday, November 25th at 8:20 PM ET, the New Orleans Saints will host the Buffalo Bills for an exciting Week 12 matchup in Caesars Superdome in New Orleans, Louisiana. The Saints are coming off a close Week 11 loss against the Philadelphia Eagles. On the other hand, the Bills are coming off of an embarrassing loss against the Indianapolis Colts. Both teams look to succeed in Week 12 and get a win.
Bills vs Saints Matchup at a Glance
- Sport: NFL
- Teams: Buffalo Bills vs New Orleans Saints
- Where: Caesars Superdome in New Orleans, Louisiana
- Date: November 25th, 2021
- Betting Odds:
- Spread: BUF -4.5 (-110) | NO +4.5 (-110)
- MoneyLine: BUF -200 | NO +170
- Total: 46.5 – Over -110 | Under -110
All odds listed are courtesy of PointsBet.
Buffalo Bills Preview: What Exactly Is Going On?
The Buffalo Bills are stacked with talent. They have an amazing Pro Bowl quarterback in Josh Allen. They have great receivers and tight ends with Stefon Diggs and Dawson Knox. However, despite all that talent, they are losing games they are favorites to win. Most of the Bills wins this year have been against weak NFL teams like the Football Team, Dolphins, Texans, Jets, etc.
The Bills are failing to do the little things. They were unable to score more than 6 points against the Jaguars and 15 points against the Colts. In order to beat the Saints, the Bills need to develop a run game. Zack Moss is not entirely healthy and Devin Singletary is playing too average. They need them both to play better so defenses know the pass is not their only option in the game.
New Orleans Saints Preview: Not Looking Great Anymore
A few weeks ago, quarterback Jameis Winston went down with an MCL and ACL injury and since that injury, it has been Trevor Siemian who has taken his place. Though Siemian is a backup, he has played well. Last week, he threw for roughly 200 yards and 3 touchdowns. However, the Saints were unable to secure the win against the Eagles.
The Saints look like they have lost hope for this season and honestly they may be correct. But if the Saints wish to win Thursday, Siemian must continue his strong play and the defense must step up. Stopping Josh Allen is not going to be easy.
Odds & Free Betting Analysis for This Football Game
The current spread is at 4.5, favoring the Buffalo Bills. Personally, I believe this game will not be closer than most predict it to be. The Bills will most likely blow the Saints out of the water because their offense, previously playing poorly, will now be a stronger point of the team. Going against this banged-up offense led by Trevor Siemian should be fairly easy for the Bills.
In terms of the MoneyLine, I believe the Bills are a definite lock.
Bills vs Saints Pick
KnupSports.com Free Betting Pick
- Spread: BUF -4.5
- MoneyLine: BUF -200
- Total: Over 46.5 (-110) (at PointsBet | at Caesars | at DraftKings | at Fanduel | at BetRivers)
Be sure to check out our other free picks and betting plays to bet on today!
Search Game & Player Props for Bills vs Saints
Use the prop finder below to find all available offerings for this Bills vs Saints game. You can also search for any player to see the props available for an individual.
Join our Discord to leave a question or comment regarding this article. We have sports fans talking betting all day — every day! JOIN THE DISCORD NOW AND QUALIFY FOR PRIZES & BETTING SWAG!