• How will the Cardinals respond after their first loss
  • Must win for the 49ers
  • Is Kyler Murray still MVP?

The Cards had a scorching hot start to the season, but recently things have gone sideways just a tad. A significant injury to J.J. Watt seems bigger than some may make it out to be, and Chandler Jones is still getting into the swing of things. It will be interesting to see how this team responds this weekend.

As for the 49ers, they are still in the hunt, but the injury bug has got them bad too as of late. Big injuries to George Kittle and Elijah Mitchell hurt this team early in the season, but it seems like they are getting healthy at the right time. Jimmy Garoppalo and company had a big win against the Bears last week and hope to keep that going.

Cardinals vs 49ers Matchup at a Glance

  • Sport: NFL
  • Teams: Arizona Cardinals at San Francisco 49ers
  • Where: San Francisco, Levi Stadium
  • Date: Sunday, November 7th
  • PS: SF +2 (-110) ARI -2 (-110)
  • ML: SF (-134) | ARI (+114)
  • O/U: 45.5
  • Betting Odds: list the spread, moneyline and total (at PointsBet | at Caesars | at DraftKings | at Fanduel | at BetRivers)

Cardinals Preview

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The Cardinal’s pass defense might not be very busy this week, but they were really solid last week. Against last year’s MVP Aaron Rodgers they only allowed 184 yards and 5.0 YPA. Not only that, their numbers this season have been in the top of the league, currently tied for second in the league when it comes to opponents YPA, keeping them to 6.3.

49ers Preview

A key for the 49ers in this game will be making things happen on the ground. The Card’s secondary is way too good to air the ball out 40 times on.

Last week starting running back, Elijah Mitchell had himself a day running for 137 yards and a touchdown. Similar production will be needed to take this one.

Odds & Free Betting Analysis for This NFL Game

I like Arizona in this game. However, the 49ers are a well-coached team. I just don’t see them having the ability to keep up with Kyler Murray and his potent offense in Arizona. Moneyline, point spread I would hammer the Cardinals.

Cardinals vs 49ers Pick

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