Read our Seahawks vs 49ers pick and preview for this NFL Wild Card Weekend game in Santa Clara. Check out who we like to win and cover the spread in this week’s NFL matchup.

Seahawks vs 49ers Pick & Preview- NFL Playoffs

On Saturday, January 14th at 4:30 PM ET, the San Francisco 49ers and Seattle Seahawks at Levi’s Stadium in Santa Clara, CA. FOX will carry the TV coverage for the game. In a matchup between two NFC West teams, the 49ers are 10.0 point favorites at home.

Seahawks vs 49ers Matchup at a Glance

  • Sport: NFL
  • Teams: Seattle Seahawks at San Francisco 49ers
  • Where: Santa Clara at Levi’s Stadium
  • Date: Saturday, January 14th
  • Betting Odds SF -10.0, SEA +382 | SF -497 O/U 42.5

Will Geno Smith And The Seahawks Keep Things Interesting vs San Francisco?

This week, the Seahawks will look to keep things rolling after picking up a 19-16 win over their division rival, the Los Angeles Rams. Seattle did not cover the spread in their win, as they entered as the -5.0 point favorites. The team’s combined scoring of 35 points fell below the posted betting line of 42.

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Offensively, Seattle found success in the run game, putting up 197 yards on 36 attempts. Individually, Kenneth Walker III compiled 114 yards, with a per-attempt average of 3.9.

At the quarterback position, Geno Smith ended the game with a passer rating of 65.6 on 213 yards through the air. Smith ended the game by throwing for 1 touchdown. Wide receiver Tyler Lockett had a big game for Seattle, coming up with 54 yards and a touchdown. As a team, Seattle ranks 12th in the number of pass yards per game, averaging 231.4 per game. This season, 54.9% of the team’s offensive plays have come through the pass, placing them 12th in the NFL.

Will The 49ers Take Care Of Business As Heavy Home Favorite?

Going back to last week, the 49ers picked up a win in the NFC West, as they defeated the 49ers by a score of 38-13. San Francisco also picked up an ATS win, with a point spread of -14.5. The teams combined for a total of 51 points, which surpassed the over-under betting line of 40.

San Francisco did a good in the run game vs Arizona, compiling 169 yards on 37 carries. Elijah Mitchell was able to find the endzone 2 times, along with his 55 yards.

Quarterback Brock Purdy struggled to move the ball in the passing game, finishing with just 178 yards through the air and a passer rating of 141.3 For the game, Purdy was able to throw for 3 touchdowns. Although Brandon Aiyuk did not come up with a touchdown grab through the air, he was still productive with 59 yards. On average, San Francisco has thrown the ball 30.1 times per game, placing them 27th in the league. This season, 48.9% of the team’s offensive plays have come through the pass, placing them 23rd in the NFL.

Odds & Free Betting Analysis for this NFL Game

Seattle will look to continue on last year’s success vs San Francisco as they won both of their matchups by scores of 30-23 and 28-21.

Looking back at the recent matchups between Seattle and San Francisco, the 49ers have taken 3 of the last 5 contests. The over-under record in these games sits at 2-3, with the average scoring total coming in at 43.8 points.

The San Francisco 49ers have performed well vs the spread in recent games, going 3-2-0. The Seahawks’ offense has averaged 20.8 points per game over the 5 most recent meetings with San Francisco, compared to the 49ers at 23.0.

When looking at their past 5 road matchups, Seattle has an ATS record of 2-3 while averaging 24.2 per game. The team went 3-2-0 overall in these games.

Across their last 5 home contests, San Francisco has been good against the spread posting a mark of 5-0. Their overall mark in these games was 5-0, while averaging 31.2 points per game.

Seahawks vs 49ers Pick

  • Free Spread Prediction: 49ers -10.0
  • Free Total Prediction: Over 42.5
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