Friday night action kicks off this latest round of games in the Premier League matchday 5, as unbeaten sides Manchester United, Chelsea, Liverpool, and Everton look to continue their excellent start to the 2021-22 campaign. We will go through all the games taking place this weekend in England’s top-flight and find the best selections that gamblers can make.

Premier League Matchday 5 Predictions 

Newcastle United vs Leeds United

Action in the Premier League gets underway with a game under the lights at St James’ Park. Both sides will be looking for a first win of the new season. Newcastle lost both games against Leeds last season, and the Whites will be looking for three straight wins against the Magpies since 1967. Newcastle have already conceded 12 goals this season, and more pressure could be put under Steve Bruce this weekend.

Pick: Leeds United (+125)

Wolves vs Brentford

Saturday’s action gets underway with a fixture between Wolves and Brentford. The hosts got their first win of the new season last weekend against Watford, while Brentford will also be searching for a second win of the 2021-22 season. Brentford have won just one of their last five meetings against Wolves, while the hosts have won three of their previous four games against the Bees.

Pick: Wolves (-110)

Norwich City vs Watford

Two of the newly promoted sides clash in the Premier League on Saturday, with both looking to steer clear of the drop zone. Watford have won three of their last four against Norwich in the top-flight, while the Canaries are yet to pick up a single point against the Hornets in the last four meetings between the sides. Norwich have problems scoring in the Premier League, hitting the back of the net just twice in their last 14 games.

Pick: Watford (+235)

Burnley vs Arsenal

Arsenal picked up a first win of the season against Norwich last weekend, while Burnley are on their longest ever run without a win at Turf Moor (12). The Clarets are unbeaten in their last three against the Gunners, but an away win looks difficult to oppose given the defensive issues that Burnley have this season.

Pick: Arsenal (+100)

Manchester City vs Southampton

Manchester City have won their last three, while Southampton have drawn their last three. City’s record against the Saints is excellent, having won eight of their last nine. The Saints also haven’t won in their last ten games at the Etihad. City have scored at least five in their last three home games. This should be the easiest bet of the weekend.

Pick: Over 3.5 Goals (-104)

Liverpool vs Crystal Palace

Liverpool can move to the top of the Premier League on Saturday. The Reds beat Leeds United 3-0 last weekend, while Palace beat Tottenham Hotspur by the same scoreline. Liverpool have won their last eight league games against the Eagles, conceding just five in the process. Home banker.

Pick: Liverpool (-500)

Aston Villa vs Everton

Everton can keep tabs on the teams at the top of the league standings with a fourth win in five games this season. Meanwhile, Villa will be looking for just a second victory. The hosts are unbeaten in four Premier League games against the Toffees, but Everton have been beaten on just two occasions in their last 17 on the road.

Pick: Everton (+195)

Brighton vs Leicester City

One of three games on Sunday will see Brighton take on Leicester. The hosts have won three games so far this season, while the Foxes have won twice and lost twice. This should be an entertaining game with goals at either end, over 2.5 goals could be the best selection.

Pick: Over 2.5 Goals (+112)

West Ham United vs Manchester United

Cristiano Ronaldo has scored three goals in two games since returning to Manchester United. However, the Red Devils will be looking to bounce back from a shock defeat against Young Boys in the Champions League in midweek. West Ham slipped to a draw on the road against Southampton last weekend. United’s away record in the league is an unbeaten run that stretches back to January 2020, and another win is likely to come here.

Pick: Manchester United to Win To Nil (+235)

Tottenham Hotspur vs Chelsea

The game of the weekend comes from the Tottenham Hotspur Stadium, as Chelsea look for a fourth win of the season. Spurs will be hoping to bounce back from defeat at Palace last weekend, but those defensive issues could hinder them once again, as the Blues look good value to win 2-0, with Romelu Lukaku adding to his tally of four in all competitions this term.

Pick: Chelsea 2-0 (+750)

All odds from PointsBet (Correct as of 09/15/21)